We travel those waters frequently.
Stuart to Melbourne 65, think you can anchor off MLB harbor.
MLB Titusville 60, TIV has anchorage by marina and moorings.
MLB New Smyrna 74 anchor in alternate channel or go on to Rockhouse creek by Ponce Inlet.maybe 80- or anchor after Mosqueto Lagoon in Edgewater area.
NSB to Palm Coast 44 miles, marina has face dock overnights.
PC to Palm Cove, much better than Beach 56
PCove to Ortega 33 check current and try to go with - 2-3 Kn makes a difference.
We did TIV to PCoast one, 75 miles, lots of wake zones, long day.
Matsanzas inlet recently dredged, well marked, Atlantic Blvd in JAX can really rip, and ICY St Johns moves, forget chart or plotter, but well marked.
Have a safe trip, Ortega is one of the best in N FL.