We "sold everything, and took off for 4 years full time cruising two times. The first time was when we were in early 40's. We kept a 10' x 10' x 10' storage, Unit, and kept some furniture, we let trusted friends take care of.
We had no trouble doing this--sold house with one week escrow--and the buyer let us stay in his condo while we sorted things out--and were ready to leave.
We were going to extend to 6 years, but my father died, and mother was blind, so we came back on schedule. We had the plan to work for 8 more years and get our kids thru college and grad school before retirement and second 4 year cruise.
We bought a new house, and sold it with furniture, shortly before we were ready to leave for the second 4 to 5 year cruise. We kept only very special items; photos, and a few pieces of good furniture. What we had would fit in a 16 x 8 x 6 foot trailer.
We had all new systems and gear on each of the boats. There were a few unexpected repairs. We ate at "native" eateries, lived pretty much on local economy, stayed away from "Tourist" places. One item not always considered is medical care--you want some insurance, or at least an evacuation policy back to the USA. We did all of our own maintenance, and understood the systems, since we installed all of them.
Your plan sounds very do-able to me. I probably would put less into the boat, but it depends on your cruising plans. Consider the re-sale of the boat. Consider if the boat is the "tool" you want for the voyages you want to make. In our case it was long distance ocean crossings, from the tropics to the arctic. So we outfitted the boats accordingly.
Do a lot of "homework" both on selection of boat and systems, as well as routes, weather, sociology of the areas, risks, and make a realistic plan.